Aaj Ka News Online: The Indian Council of Medical Research (ICMR) has recommended the use of the standard Q COVID-19 AG antigen detection test in zone and healthcare settings in conjunction with RT-PCR testing. The assembled NASA swab is used for testing in this process.
“A positive test in the antigen, with results available in 30 minutes, should be considered a positive test and do not require reaffirmation by RT-PCR testing. It will show whether the patient is currently infected, ”L.K. Sharma, Scientific and Media Coordinator, ICMR, on Monday.
The kit validated by the ICMR and the All India Institute of Medical Sciences (AIIMS) was different from the Rapid Antibody Test Kit. “The sample in this test is nasopharyngeal swab, while blood is collected in the antibody test. The kit will allow rapid diagnosis, ” he said.
The standard Q COVID-19 Ag detection kit is a rapid chromatographic immunoassay for the qualitative detection of antigens specific to SARS-CoV-2. It has been developed by South Korea-based company SD Biosensor, which has a manufacturing unit in Manesar, Gurugram.
An advisory issued by the ICMR states that given the high specificity (ability to detect true negativity) and relatively low sensitivity, the council uses this to test for symptomatic individuals with influenza-like illness and asymptomatic. Use this test in content zones or hotspots. And Aaj Ka News Online, Direct and high-risk contact with co-morbidities of a confirmed case.
“The test should be conducted once between five and ten days of exposure to such individuals,” the ICMR said. In health care settings, all symptomatic patients with influenza-like illness, patients undergoing chemotherapy, patients with malignant disease, and elderly patients can be tested using this kit, it is noted.
“The test can be interpreted as positive or negative 15 minutes after the specimen is placed in the well in the presence of test and control lines, which can be read with the naked eye without the need for any special equipment. The maximum duration to interpret a positive or negative test is 30 minutes. After that, the test strip should be discarded. The ICMR stated that test kits should be stored between 2 ° to 30 ° C.
“Specificity ranged from 99.3 to 100% at the two sites and the sensitivity of the test [i.e. the ability to detect true positives] ranged from 50.6% to 84% in two independent evaluations depending on the patient’s viral load. The higher viral load was the higher the sensitivity. Is correlated with, “it added.